LAIR1 Antibody (Center) Blocking peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 3903
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: LAIR1
Other Names: Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305
Availability: 2 weeks
Bio Background: The protein encoded by this gene is an inhibitory receptorfound on peripheral mononuclear cells, including NK cells, T cells,and B cells. Inhibitory receptors regulate the immune response toprevent lysis of cells recognized as self. The gene is a member ofboth the immunoglobulin superfamily and the leukocyte-associatedinhibitory receptor family. The gene maps to a region of 19q13.4called the leukocyte receptor cluster, which contains at least 29genes encoding leukocyte-expressed receptors of the immunoglobulinsuperfamily.
Bio References: Davila, S., et al. Genes Immun. 11(3):232-238(2010)Brondijk, T.H., et al. Blood 115(7):1364-1373(2010)Tang, X., et al. J. Immunol. 182(9):5446-5452(2009)Lebbink, R.J., et al. Matrix Biol. 28(4):202-210(2009)Xue, J.N., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24(4):373-374(2008)
Primary Accession: Q6GTX8
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP13784c was selected from the Center region of LAIR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.