TN8-H5250-100ug TN8-H5250-1mg
Human CD30 / TNFRSF8 Protein, Llama IgG2b Fc Tag, low endotoxin
ACROBiosystems
DESCRIPTION
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
DETAILS
- Tag: C-LlamaFc(LlamaIgG2b)
- Host: HEK293
- Size: 1mg
- Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
- Format: Powder
- Purity: 95%
- Source: Human CD30 Protein, Llama IgG2b Fc Tag (TN8-H5250) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
- Storage: -20℃
- Category: Immune Checkpoint Proteins
- Molecule: CD30
- Accession: NP_001234.2
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Phe 19 - Lys 379
- Swiss-prot: P28908-1(C297R)
- Package Size: 500ug*2
- Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 66.3 kDa. The protein migrates as 95-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 0.01 EU per μg
- Molecular Weight: 66.3 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html