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T39909

XZ739

TargetMol

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DETAILS

  • Cas: 2365172-19-4
  • Purity: 98%
  • Smiles: CN(CCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1 |t:81|
  • Category: Compound
  • Molecular Weight: 1349.99
  • Molecular Formula: C65H76ClF3N8O12S3

DESCRIPTION

XZ739 is a Cereblon-dependent PROTAC BCL-XL degrader, targeting a member of the Bcl-2 family, with a DC50 value of 2.5 nM in MOLT-4 cells after 16 hours of treatment. Additionally, XZ739 elicits cell death via caspase-mediated apoptosis.

Lead Time: 4 - 5 weeks

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