DESCRIPTION

• Shiptemp: -80°C (dry ice)
• Synonyms: COVID-19 assay kit, SARS assay kit, Coronavirus screening kit
• Category: Coronavirus/Assay Kit
• Background: Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyzes the conversion of angiotensin II to angiotensin 1-7 and L-phenylalanine. Angiotensin II is part of the classical renin angiotensin system (RAS), a hormone system that regulates fluid balance, blood pressure and maintains vascular tone. ACE2 has been also proved to be the receptor for the human respiratory coronavirus NL63, the SARS-coronavirus (SARS-CoV) and the novel coronavirus 2019-nCoV/SARS-CoV-2.
• References: Danilczyk, U., et al. Circulation Research. 2006. 98(4): 463-471.Ge, X. Y., et al. Nature. 2013. 503(7477): 535-538.
• Description: The ACE2 Inhibitor Screening Assay Kit is designed to measure the exopeptidase activity of ACE2 for screening and profiling applications. 
• Methodology: Fluorogenic
• Supplied As: The ACE2 assay kit comes in a convenient 96-well format, with purified ACE2, its substrate, and ACE2 buffer for 96 reactions.
• Unspsc Code: 41105331
• Unspsc Name: Protein chemifluorescent detection reagents or kits or substrates
• Applications: Useful for studying enzyme kinetics and screening small molecule inhibitors and antibodies for drug discovery and HTS applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 81090, 11003, 79931, 79936, 79959
• Storage Stability: Up to 6 months from date of receipt, when stored as recommended.
• Scientific Category: Protease
• Instructions for Use: See assay protocol for detailed instructions.