DMRT2 Blocking Peptide (N-Term)

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 10655
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: DMRT2
Other Names: Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL-2, DMRT2, DSXL2
Availability: 2 weeks
Bio Background: Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
Bio References: Raymond C.S.,et al.Hum. Mol. Genet. 8:989-996(1999). Ottolenghi C.,et al.Genomics 64:179-186(2000). Calvari V.,et al.Genomics 65:203-212(2000). Humphray S.J.,et al.Nature 429:369-374(2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Primary Accession: Q9Y5R5
Targetspecificity: The synthetic peptide sequence is selected from aa 242-256 of HUMAN DMRT2