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40321

EGFR Kinase Assay Kit

BPS Bioscience

DESCRIPTION

The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cell-surface receptor for members of the epidermal growth factor family. Overexpression and/or hyperactivation of EGFR kinase is associated with several human cancers such as lung, glioblastoma, and epithelian tumors of the neck and head, leading to the development of anticancer therapeutics targeting EGFR. The EGFR Kinase Assay Kit is designed to measure EGFR Kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The EGFR Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant EGFR enzyme, EGFR substrate, ATP and kinase assay buffer for 100 enzyme reactions.

DETAILS

  • Shiptemp: -80°C (dry ice)
  • Synonyms: EGFR, ErbB-1, HER1
  • Warnings: Avoid freeze/thaw cycles.
  • Category: Kinase/Assay Kit
  • References: Nakamura, J.L. Expert Opin. Ther. Targets 11(4):463-472 (2007)
  • Description: The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cell-surface receptor for members of the epidermal growth factor family. Overexpression and/or hyperactivation of EGFR kinase is associated with several human cancers such as lung, glioblastoma, and epithelian tumors of the neck and head, leading to the development of anticancer therapeutics targeting EGFR. The EGFR Kinase Assay Kit is designed to measure EGFR Kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The EGFR Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant EGFR enzyme, EGFR substrate, ATP and kinase assay buffer for 100 enzyme reactions.
  • Methodology: Chemiluminescent
  • Unspsc Code: 41105332
  • Unspsc Name: Protein chemiluminescent detection reagents or kits or substrates
  • Applications: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
  • Product Type: Assay Kit
  • Biosafety Level: Not applicable (BSL-1)
  • Related Products: 40322, 40323, 40324, 40326, 78487
  • Storage Stability: Up to 6 months when stored as recommended.
  • Scientific Category: Kinase