SMC-343D-BI
Scientist.com Supplier
TRPC7 Antibody, Clone N64A/36: Biotin
Stressmarq Biosciences
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DESCRIPTION
Mouse Anti-Human TrpC7 Monoclonal IgG1
DETAILS
- Target: TRPC7
- Gene Id: 57113
- Isotype: IgG1
- Conjugate: Biotin
- Immunogen: Synthetic peptide amino acids 845-862 of human TRPC7
- References: 1. Numaga T., Wakamori M., and Mori Y. (2007) Handb Exp Pharmacol. 179: 143-151. 2. Satoh S., et al. (2007) Mol Cell Biochem. 294(1-2): 205-215.
- Swiss-prot: Q9HCX4
- Specificity: Detects ~100kDa.
- Applications: WB | IHC | ICC/IF | IP | AM
- Clone Number: N64A/36 (Formerly sold as S64A-36)
- Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Host Species: Mouse
- Product Type: Monoclonal
- Purification: Protein G Purified
- Concentration: 1 mg/ml
- Research Areas: Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels | Cell Signaling
- Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
- Accession Number: NP_065122.1
- Alternative Names: TRP7 Antibody, KNP3 Antibody, TRPM2 Antibody, transient receptor potential cation channel subfamily C member 7 Antibody
- Antibody Dilution: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
- Cite This Product: StressMarq Biosciences Cat# SMC-343D-BI, RRID: AB_2700713
- Immunogen Species: Human
- Storage Temperature: Conjugated antibodies should be stored according to the product label
- Shipping Temperature: Blue Ice or 4ºC
- Cellular Localization: Membrane
- Scientific Background: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).
- Certificate of Analysis: 1 µg/ml of SMC-343 was sufficient for detection of TrpC7 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Species Reactivity Full Name: Human | Mouse | Rat