mouse monoclonal IgG1; SR-3B Antibody (H-9) is an IgG1 κ mouse monoclonal SR-3B antibody (also designated HTR3B antibody, 5HT3B antibody antibody, 5-Hydroxytryptamine Receptor 3B antibody, 5-HT3B antibody, 5-Hydroxytryptamine (Serotonin) Receptor 3B Ionotropic antibody, 5-HT3-B antibody, 5-Hydroxytryptamine (Serotonin) Receptor 3B antibody, or 5-Hydroxytryptamine 3 Receptor B Subunit antibody) that detects the SR-3B protein of mouse, rat and human origin by WB, IP, IF and ELISA. SR-3B Antibody (H-9) is available as both the non-conjugated anti-SR-3B antibody form, as well as multiple conjugated forms of anti-SR-3B antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Serotonin is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it modulates several processes including psychiatric disorders, cardiovascular function and motility of the gastrointestinal tract. Serotonin receptors (also designated 5-hydroxytryptamine or 5-HT receptors) are members of the G protein-coupled receptor family that mediate the effects of serotonin. The serotonin receptors (alternatively designated SR) include SR-1, SR-2, SR-3, SR-4, SR-5, SR-6 and SR-7. The SR-1 receptors are subdivided into SR-1A, B, C, D, E and F receptors, while the SR-2 receptors comprise three subtypes: SR-2A, B and C. SR-3 is divided into SR-3A and SR-3B, a 441 amino acid protein with 41% sequence homology to SR-3A. SR-3B is responsible for fast, depolarizing responses in neurons after activation. The SR-3B protein is expressed in kidney and brain, specifically in hippocampus, thalamus and caudate nucleus, and particularly in amygdala. No expression of SR-3B is detected in heart, placenta, lung, liver, skeletal muscle or pancreas.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.