RP01732
Recombinant Mouse EPO-R/Epor Protein
ABclonal
DESCRIPTION
Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type a… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
DETAILS
- Tag: C-6His
- Source: HEK293 cells
- Gene Id: 13857
- Species: Mouse
- Lead Time: 3-5 weekdays
- Swiss Prot: P14753
- Research Areas: Other Recombinant Protein
- Alternative Names: EPO-R;Epor
Equivalent Items
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