12-9301
Anti-BAFF-R antibody(DM127), Rabbit mAb
Abeomics
DESCRIPTION
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell surviva
DETAILS
- App Id: FACS
- Antigen: BAFF-R
- Format Id: Liquid
- Clone Name: DM127
- Host Animal: Rabbit
- Clonality Id: Monoclonal
- Purification: Purified from cell culture supernatant by affinity chromatography
- Reactivity Id: Human
- Alternative Name: BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin
- Application Note: FACS 1/100
- Storage Condition: Store at -20°C for 12 months (Avoid repeated freezing and thawing)