Anti-TUG Antibody [JE59-09]

DESCRIPTION

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: Q9BZE9 Human;SwissProt: Q8VBT9 Mouse
Clone Id: JE59-09
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: Alveolar soft part sarcoma chromosomal region candidate gene 1 protein antibody Alveolar soft part sarcoma chromosome region candidate 1 (human) antibody Alveolar soft part sarcoma locus antibody ASPC antibody ASPC1_HUMAN antibody ASPCR 1 antibody ASPCR1 antibody ASPL antibody ASPS antibody ASPSCR 1 antibody Aspscr1 antibody FLJ45380 antibody RCC 17 antibody RCC17 antibody renal cell carcinoma gene on chromosome 17 antibody renal cell carcinoma papillary 17 antibody Renal papillary cell carcinoma protein 17 antibody Tether containing a UBX domain for GLUT4 antibody Tether containing UBX domain for GLUT4 antibody TUG antibody UBX domain containing protein 9 antibody UBX domain protein 9 antibody UBX domain-containing protein 9 antibody UBXD 9 antibody UBXD9 antibody UBXN 9 antibody UBXN9 antibody
Application: WB,IHC-P
Epitope Region: Recombinant protein within human TUG aa 151-350/553.
Protein Target: ASPSCR1
Target Species: Human,Mouse,Rat
Species Reactivity: Human,Mouse,Rat