T2310
CHIR-99021
TargetMol
DETAILS
- Cas: 252917-06-9
- Purity: 98.91%
- Smiles: ClC1=C(C=2C(=CN=C(NCCNC3=CC=C(C#N)C=N3)N2)C=4NC(C)=CN4)C=CC(Cl)=C1
- Category: Compound
- Molecular Weight: 465.34
- Molecular Formula: C22H18Cl2N8
DESCRIPTION
CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.
Lead Time: 4 - 5 weeks
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