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T35483

19,20-Epoxycytochalasin D

TargetMol

- Open Babel Depiction O H 3 C O O CH 3 OH CH 3 OH H 3 C H 2 C N H O O

DESCRIPTION

19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for both) without inducing cytotoxicity in Vero cells. It is cytotoxic to BT-549, LLC-PK11, and P388 cells (IC50s = 7.84, 8.4, and 0.16 µM, respectively) but not SK-MEL, KB, or SKOV3 cells up to a concentration of 10 µM.

DETAILS

  • Cas: 191349-10-7
  • Purity: 98%
  • Smiles: [H][C@@]12O[C@@]1([H])[C@@](C)(O)C(=O)[C@@H](C)C\C=C\[C@@]1([H])[C@H](O)C(=C)[C@@H](C)[C@@]3([H])[C@H](Cc4ccccc4)NC(=O)[C@@]13[C@@H]2OC(C)=O |t:14|
  • Category: Compound
  • Molecular Weight: 523.626
  • Molecular Formula: C30H37NO7

Lead Time: 4 - 5 weeks

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