UMI-77

DESCRIPTION

UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.

DETAILS

Purity: >98%
Smiles: O=C(O)CSC1=CC(NS(=O)(C2=CC=C(Br)C=C2)=O)=C3C=CC=CC3=C1O
Category: Reference compound
Lead Time: 1-2 days
Cas Number: 518303-20-3
Molecular Weight: 468.34
Molecular Formula: C18H14BrNO5S2

Lead Time: 1 - 2 weeks