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Human SIgMa Non-opioid Intracellular Receptor 1, SIgMAR1 ELISA Kit

Bioassay Technology Laboratory


Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (PubMed:16472803, PubMed:9341151). Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria. Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112 (By similarity).


  • GeneID: 10280
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 25,128
  • Synonyms: Aging-associated gene 8 protein;ALS16;DSMA2;hSigmaR1;OPRS1;SIG-1R;Sigma 1-type opioid receptor;Sigma non-opioid intracellular receptor 1;sigma1R;Sigma1-receptor;SIGMAR1;SR31747-binding protein;SRBP;SR-BP
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: SIGMAR1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.026ng/mL
  • Target Protein: SIGMAR1
  • Detection Range: 0.05-20ng/mL
  • Full Product Name: Sigma non-opioid intracellular receptor 1
  • Standard Solution: 24ng/mL
  • UniProt Accession: Q99720