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Recombinant Human GDF-7



GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissues. Recombinant Human GDF-7 is a 28.0 kDa disulfide-linked homodimer containing two 129 amino acid residues.


  • Gene Id: 151449
  • Uniprot: Q7Z4P5
  • Activity: Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.
  • Category: RUO Cytokines
  • Subcategory: Growth Factors & Cytokines
  • Research Areas: Bone, Skeletal, Cartilage, Cell Culture, Immune System, Neurobiology, TGF-beta Superfamily
  • Alternative Names: Growth/Differentiation Factor-7, BMP-12
  • Species of Origin: Human
  • Expression System Source: E.coli