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37748

SB-4

Cayman Chemical

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DESCRIPTION

An activator of BMP4 signaling; induces BMP4 signaling in a reporter assay using HEK293 cells expressing a recombinant human BMP4 response element (EC50 = 74 nM); increases phosphorylation of SMAD1, -5, and -9 in HEK293 cells at 10 µM; induces Blimp1 and Tfap2c expression in mouse embryonic stem cells

DETAILS

  • Inchi: InChI=1S/C14H10BrNOS/c15-11-7-5-10(6-8-11)9-18-14-16-12-3-1-2-4-13(12)17-14/h1-8H,9H2
  • Purity: ≥98%
  • Raptas: Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling||Research Area|Cell Biology|Stem Cell Research|Differentiation
  • Smiles: BrC1=CC=C(CSC2=NC3=C(O2)C=CC=C3)C=C1
  • Inchikey: JDVOIBFEFVKUPL-UHFFFAOYSA-N
  • Cas Number: 100874-08-6
  • Formulation: A solid
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C14H10BrNOS
  • Formula Weight: 320.2
  • Shelf Life Days: 1460