IL-5, Mouse(CHO-expressed)

DESCRIPTION

Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.

DETAILS

Form: Lyophilized
Purity: > 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Species: Mouse
Product Line: Cytokines
Expression System: CHO
Storage Stability: Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Biological Activity: ED50 < 0.5 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 2.0 × 106 units/mg.
Protein Construction: IL-5 (Met21-Gly133)\nAccession # P04401