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Recombinant Murine IL-10



IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-alpha. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.


  • Gene Id: 16153
  • Uniprot: P18893
  • Activity: PeproTech's Murine IL-10 is fully biologically active as measured by the dose-dependent co-stimulation (with IL-4) of the proliferation of murine MC/9 cells. The ED50 was found to be ≤ 2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg.
  • Category: RUO Cytokines
  • Subcategory: Growth Factors & Cytokines
  • Research Areas: AIDS/HIV, Cancer, Immune System, Inflammation, Neurobiology, Stem Cells and Differentiation, Allergy, Transplantation, COVID-19
  • Alternative Names: B-TCGF, CSIF, TGIF
  • Species of Origin: Murine
  • Expression System Source: E.coli