R1510-34
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Anti-HLA-DR Antibody
HuaBio
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DESCRIPTION
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
DETAILS
- Host: Rabbit
- Type: Primary
- Uniprot: SwissProt: P01903 Human
- Clonality: Rabbit polyclonal Antibody
- Conjugate: Non-conjugated
- Alias Names: DASS-397D15.1 antibody DR alpha chain antibody DR alpha chain precursor antibody DRA_HUMAN antibody DRB1 antibody DRB4 antibody FLJ51114 antibody Histocompatibility antigen HLA DR alpha antibody Histocompatibility antigen HLA-DR alpha antibody HLA class II histocompatibility antigen antibody HLA class II histocompatibility antigen DR alpha chain antibody HLA DR1B antibody HLA DR3B antibody HLA DRA antibody HLA DRA1 antibody HLA DRB1 antibody HLA DRB3 antibody HLA DRB4 antibody HLA DRB5 antibody HLA-DR histocompatibility type antibody HLA-DRA antibody HLADR4B antibody HLADRA1 antibody HLADRB antibody Major histocompatibility complex class II DR alpha antibody Major histocompatibility complex class II DR beta 1 antibody Major histocompatibility complex class II DR beta 3 antibody Major histocompatibility complex class II DR beta 4 antibody Major histocompatibility complex class II DR beta 5 antibody MGC117330 antibody MHC cell surface glycoprotein antibody MHC class II antigen DRA antibody MHC II antibody MLRW antibody OTTHUMP00000029406 antibody OTTHUMP00000029407 antibody
- Application: WB,IF-Cell,IHC-P,FC
- Epitope Region: Synthetic peptide within C-terminal human HLA-DR.
- Protein Target: HLA-DRA
- Target Species: Human,Mouse
- Species Reactivity: Human,Mouse