10008593
PSN375963
Cayman Chemical
DESCRIPTION
PSN375963 is a potent and selective agonist of GPR119 that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 8.4 and 7.9 µM, respectively (EC50 values for OEA are 3.2 and 2.9 µM, respectively).{14046} These data suggest that PSN375963 may be useful as a therapeutic agent for the treatment of obesity.
DETAILS
- Inchi: InChI=1S/C17H23N3O/c1-2-3-4-13-5-7-15(8-6-13)17-19-16(20-21-17)14-9-11-18-12-10-14/h9-13,15H,2-8H2,1H3
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Neuroscience
- Smiles: CCCCC1CCC(CC1)c1onc(n1)c1ccncc1
- Inchikey: OAVLEYPTWABFLF-UHFFFAOYSA-N
- Cas Number: 388575-52-8
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C17H23N3O
- Formula Weight: 285.4
- Shelf Life Days: 730