IGB-L5204-200ug IGB-L5204-1mg
Llama IgG2b Fc Protein, Tag Free (MALS verified)
ACROBiosystems
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DESCRIPTION
Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis. Ig gamma-2 chain Fc region contains two constant regions of IgG2 H chain (CH2, CH3).
DETAILS
- Tag: Native
- Host: HEK293
- Size: 200ug
- Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
- Format: Powder
- Purity: 90%
- Source: Llama IgG2b Fc, Tag Free (IGB-L5204) is expressed from human 293 cells (HEK293). It contains AA Glu 1-Ser 243 (Accession # AAX73259.1).
- Storage: -20℃
- Category: Other Recombinant Proteins
- Molecule: IgG2b Fc
- Accession: AAX73259.1
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Glu 1-Ser 243
- Package Size: 200ug*1
- Characteristics: This protein carries no "tag". The protein has a calculated MW of 27.3 kDa. The protein migrates as 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 27.3 kDa
- Shipping Condition: RT
- Species Reactivity: Llama
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html