MOB4A Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 92597
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: MOB1B
Other Names: MOB kinase activator 1B, Mob1 homolog 1A, Mob1A, Mob1B, Mps one binder kinase activator-like 1A, MOB1B, MOB4A, MOBKL1A
Availability: 2 weeks
Bio Background: MOB4A is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Mob4A regulates NDR1 and NDR2 kinase activity, widely expressed nuclear serine-threonine kinases that have been implicated in cell proliferation and/or tumor progression.
Bio References: Bichsel,S.J.,J. Biol. Chem. 279 (34), 35228-35235 (2004)Devroe,E.,J. Biol. Chem. 279 (23), 24444-24451 (2004)
Primary Accession: Q7L9L4
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7031a was selected from the N-term region of human MOB4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.