B73-H5253-100ug B73-H5253-1mg
Human B7-H3 / CD276 Protein, Fc Tag (MALS verified)
ACROBiosystems
Image
![](https://www.acrobiosystems.com/static/main/products/images/sds/B73-H5253.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/B73-H5253-E1.jpg)
Image
![](https://www.acrobiosystems.com/static/main/products/images/elisa/B73-H5253-E1.jpg)
DESCRIPTION
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
DETAILS
- Tag: C-Fc
- Host: HEK293
- Size: 1mg
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 95%
- Source: Human B7-H3 Protein, Fc Tag (B73-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2).
- Storage: -20℃
- Category: Immune Checkpoint Proteins
- Molecule: B7-H3
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Leu 29 - Pro 245
- Swiss-prot: Q5ZPR3-2
- Package Size: 250ug*4
- Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.9 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 49.9 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html