11629-H02H
Human AGER / RAGE Protein (Fc Tag)
Sino Biological
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DESCRIPTION
A DNA sequence encoding the human AGER isoform 1 (NP_001127.1) extracellular domain (Met 1-Ala 344) was fused with the Fc region of human IgG1 at the C-terminus.
DETAILS
- Tag: C-human IgG1-Fc
- Purity: > 70 % as determined by SDS-PAGE
- Source: HEK293 Cells
- Species: Human
- Storage: Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Activity: Measured by its binding ability in a functional ELISA. Immobilized human S100A12 at 2 μg/ml (100 μl/well) can bind recombinant human AGER with a linear range of 0.032-20 μg/ml.
- Molecule: AGER
- Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
- Lead Time: 1-3 days
- Formulation: Lyophilized from sterile PBS, pH 7.4
- Molecular Mass: The recombinant human AGER/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 562 amino acids and predictes a molecular mass of 61.1 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhAGER/Fc monomer is approximately 80-90 kDa due to glycosylation.
- Reconstitution: A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
- Accession Number: NP_001127.1
- Predicted N Terminal: Gln 24