DESCRIPTION

• Notes: Troubleshooting Guide: Visit bpsbioscience.com/assay-kits-faq for detailed troubleshooting instructions. For all further questions, please email support@bpsbioscience.com
• Shiptemp: -80°C (dry ice)
• Synonyms: ROS, c-Ros Oncogene 1, MCF3, MCF3 kit, ROS kit, ROS assay kit, MCF3 assay kit
• Warnings: Avoid freeze/thaw cycles.
• Category: Kinase/Assay Kit
• References: 1. Davies, Kurtis D., and Doebele , Robert C. "Molecular pathways: ROS1 fusion proteins in cancer." Clinical Cancer Research 15 (2013): 4040-4045.2. Davies, Kurtis D., et al. "Identifying and targeting ROS1 gene fusions in non-small cell lung cancer." Clinical Cancer Research 17 (2012): 4570-4579.3. Rimkunas, Victoria M., et al. "Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion." Clinical Cancer Research16 (2012): 4449-4457.
• Description: The ROS1 Kinase Assay Kit is designed to measure ROS1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The signal is measured using a luminometer or a microplate reader capable of reading chemiluminescence.
• Methodology: Chemiluminescent
• Supplied As: The ROS1 Kinase Assay Kit comes in a convenient 96-well format, with enough purified ROS1, substrate IGF-1Rtide, ATP, and kinase assay buffer for 96 enzyme reactions.
• Unspsc Code: 41105332
• Unspsc Name: Protein chemiluminescent detection reagents or kits or substrates
• Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
• Product Type: Assay Kit
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 40268, 79566, 79549, 79605, 78487
• Storage Stability: This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
• Scientific Category: Kinase