Human Gastrin-71 Protein, Fc tag

DESCRIPTION

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 25ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human Gastrin-71 Protein, Fc tag (GAN-H5253) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Phe 92 (Accession # P01350-1).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: Gastrin-71
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 22 - Phe 92
Swiss-prot: P01350-1
Package Size: 25ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 34.5 kDa. The protein migrates as 33-35 kDa and 40 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 34.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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