CFD-R5255-100ug CFD-R5255-1mg
Rhesus macaque Complement Factor D / CFD Protein, Fc Tag
ACROBiosystems
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DESCRIPTION
Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
DETAILS
- Tag: C-Fc
- Host: HEK293
- Size: 100ug
- Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
- Format: Powder
- Purity: 95%
- Source: Rhesus macaque Complement Factor D, Fc Tag (CFD-R5255) is expressed from human 293 cells (HEK293) and inactive. It contains AA Ile 26 - Ala 253 (Accession # H9EXC1-1).
- Storage: -20℃
- Category: Enzymes
- Molecule: Complement Factor D
- Accession: XP_005587397.1
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Ile 26 - Ala 253
- Swiss-prot: H9EXC1-1
- Package Size: 100ug*1
- Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 51.0 kDa
- Shipping Condition: RT
- Species Reactivity: Rhesus macaque
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html