Rhesus macaque Complement Factor D / CFD Protein, Fc Tag

DESCRIPTION

Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 100ug
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Format: Powder
Purity: 95%
Source: Rhesus macaque Complement Factor D, Fc Tag (CFD-R5255) is expressed from human 293 cells (HEK293) and inactive. It contains AA Ile 26 - Ala 253 (Accession # H9EXC1-1).
Storage: -20℃
Category: Enzymes
Molecule: Complement Factor D
Accession: XP_005587397.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ile 26 - Ala 253
Swiss-prot: H9EXC1-1
Package Size: 100ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 51.0 kDa
Shipping Condition: RT
Species Reactivity: Rhesus macaque
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