E1809Hu
Scientist.com Supplier
Human Latent Transforming Growth Factor Beta Binding Protein 1, LTBP1 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed: 2022183, PubMed: 8617200, PubMed: 8939931). Associates specifically via disulfide bonds with the Latency-associated Peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed: 8617200, PubMed: 8939931, PubMed: 15184403). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (PubMed: 22278742).
DETAILS
- Gene Id: 4052
- Uniprot: Q14766
- Lead Time: 3 days
- Assay Type: Sandwich
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 0.023ng/ml
- Detection Range: 0.05-20ng/ml
- Detection Method: ELISA
- Species Reactivity: Human