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Human Latent Transforming Growth Factor Beta Binding Protein 1, LTBP1 ELISA Kit

Bioassay Technology Laboratory


Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed: 2022183, PubMed: 8617200, PubMed: 8939931). Associates specifically via disulfide bonds with the Latency-associated Peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed: 8617200, PubMed: 8939931, PubMed: 15184403). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (PubMed: 22278742).


  • Gene Id: 4052
  • Uniprot: Q14766
  • Lead Time: 3 days
  • Assay Type: Sandwich
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.023ng/ml
  • Detection Range: 0.05-20ng/ml
  • Detection Method: ELISA
  • Species Reactivity: Human