Biotinylated Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS&SPR verified)

DESCRIPTION

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

DETAILS

Tag: C-10×His & C-Avi | Native
Host: HEK293
Size: 25ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Biotinylated Rabbit FCGRT&B2M Heterodimer Protein, His,Avitag&Tag Free (FCM-R82W6) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Val 297 (FCGRT) & Val 22 - Tyr 120 (B2M) (Accession # ABY47597.1 (FCGRT) & ALR85722.1 (B2M)).
Storage: -20℃
Category: MABSol® Biotin Labeled Proteins
Molecule: FcRn (FCGRT & B2M)
Accession: ABY47597.1 (FCGRT) & ALR85722.1 (B2M)
Conjugate: Biotin-labeled
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ala 24 - Val 297 (FCGRT) & Val 22 - Tyr 120 (B2M)
Package Size: 25ug*1
Characteristics: Biotinylated Rabbit FCGRT&B2M Heterodimer Protein, His,Avitag&Tag Free, produced by co-expression of FCGRT and B2M, has a calculated MW of 33.8 kDa (FCGRT) & 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) and subunit Beta-2 microglobulin (B2M) contains no tag at the C-terminus. The reducing (R) protein migrates as 35-40 kDa (FCGRT) & 12 kDa (B2M) respectively due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 33.8 kDa (FCGRT) & 11.7 kDa (B2M)
Shipping Condition: RT
Species Reactivity: Rabbit
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html