4723153-25mg 4723153-10mg
Kartogenin
Biogems
DESCRIPTION
Kartogenin binds to filamin A, an actin-binding protein, and inhibits its interaction with core-binding factor Beta. This interaction is reported to induce cartilage differentiation and potently induce human mesenchymal stem cells into chondrocytes.
DETAILS
- Purity: ≥98%
- Synonyms: 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoic acid, N-Biphenyl-4-yl-phthalamic acid, ST50171256
- Cas Number: 4727-31-5
- References: Marini, J. C., & Forlino, A. (2012). Replenishing cartilage from endogenous stem cells. New England Journal of Medicine, 366(26), 2522-2524. Hayek, A., Kerstetter-Fogle, A. E., Sachlos, E., & Bollenbach, T. (2012). Kartogenin: a game-changer in regenerative medicine. Regenerative medicine, (7), 475. Ray, K. (2012). Therapy: Tissue engineering: harnessing stem cells in cartilage repair. Nature Reviews Rheumatology, 8(6), 308-308.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: 2-[(4-phenylphenyl)carbamoyl]benzoic acid
- Molecular Weight: 317.3
- Molecular Formula: C20H15NO3
- Storage Conditions: Product should be kept at -20°C.
- Pubchem Openeye Can Smiles: C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O