S1N-C82E4-25ug S1N-C82E4-200ug
Biotinylated SARS-CoV-2 Spike S1 Protein (T95I, G142D, E154K, L452R, E484Q, D614G, P681R), His,Avitag™
ACROBiosystems
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DESCRIPTION
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
DETAILS
- Tag: C-10×His & C-Avi
- Host: HEK293
- Size: 25ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 90%
- Source: Biotinylated SARS-CoV-2 Spike S1, His,Avitag (S1N-C82E4) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). The mutations (T95I, G142D, E154K, L452R, E484Q, D614G, P681R, Q1071H) were identified in the SARS-CoV-2 Kappa variant (Pango lineage: B.1.617.1; other names: 21A/S:154K).
- Storage: -20℃
- Category: MABSol® Biotin Labeled Proteins
- Molecule: Spike S1
- Accession: QHD43416.1
- Conjugate: Biotin-labeled
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Exp Region: Val 16 - Arg 685
- Package Size: 25ug*1
- Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 78.7 kDa. The protein migrates as 90-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 78.7 kDa
- Shipping Condition: RT
- Species Reactivity: SARS-CoV-2
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html