T60249
RhlR antagonist 1
TargetMol
DESCRIPTION
RhlR antagonist 1 is a highly effective antagonist of the RhlR protein, showing an IC50 value of 26 μM. It exhibits selective antagonistic activity against RhlR, with minimal effect on LasR and PqsR. RhlR antagonist 1 strongly inhibits biofilm formation in both static and dynamic environments and reduces the production of virulence factors, such as rhamnolipid and pyocyanin, in P. aeruginosa. These characteristics make RhlR antagonist 1 a valuable tool for the development of molecules that modulate quorum sensing and control P. aeruginosa infections [1].
DETAILS
- Purity: 98%
- Smiles: #N/A
- Category: Compound
- Molecular Weight: 208.2
- Molecular Formula: C12H10F2O
Lead Time: 4 - 5 weeks
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