T71525
AB05831
TargetMol
DETAILS
- Cas: 105265-96-1
- Purity: 98%
- Smiles: N(C(C)=O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)NC1
- Category: Compound
- Molecular Weight: 204.22
- Molecular Formula: C8H16N2O4
DESCRIPTION
AB05831, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of beta-hexosaminidase. N-Acetyl-3-hexosaminidase (HEX) is a member of lysosomal hydrolases, which catalyzes hydrolysis of terminal, non-reducing N-acetyl-|3-D-glucosamine (GlcNAc) andN-acetyl-(3-D-galactosamine (GalNAc) residues in glycoproteins, gan-gliosides, and glycosaminoglycans (GAGs). HEX, released by chondrocytes into the extracellular compartment, promotes cartilage matrix degradation. Osteoarthritis patients have increased HEX activity in synovial fluid.
Lead Time: 4 - 5 weeks
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