Human CCR4 Full Length Protein, Flag,His Tag (Detergent)

DESCRIPTION

C-C chemokine receptor type 4 is a receptor for the following CC chemokines: CCL2, CCL4, CCL5, CCL17, CCL22, belongs to the G protein-coupled receptor family. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. CCR4 is often expressed on leukemic cells in cutaneous T-cell lymphoma (CTCL). Mogamulizumab is a humanized monoclonal antibody targeted at CCR4and is an investigational drug for CTCL.

DETAILS

Tag: N-Flag & C-10×His
Host: HEK293
Size: 20ug
Buffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS,pH7.5
Format: Liquid
Purity: 80%
Source: Human CCR4 Full Length Protein, Flag,His Tag (CC4-H52D3) is expressed from human 293 cells (HEK293). It contains AA Asn 2 - Leu 360 (Accession # P51679-1).
Storage: -70℃
Category: Bio-Markers & CD Antigens
Molecule: CCR4
Conjugate: Unconjugated
Stability: ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Exp Region: Asn 2 - Leu 360
Swiss-prot: P51679-1
Package Size: 20ug*1
Characteristics: This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.3 kDa.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 60.3 kDa
Shipping Condition: Dry ice
Species Reactivity: Human
Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html