Human TGF-beta RI Protein, Fc Tag (MALS verified)

DESCRIPTION

TGF type I receptor also called the activin receptor-like kinase 5 (ALK5) and involved in TGF signaling. TGFβ signaling is mediated by the interaction of TGFβ ligands (TGFβ 1, 2 or 3) with cell surface receptors, the TGF type I, type II and type III receptors. Signaling is initiated by binding of TGF to the TGF type II receptor forming a ligand-receptor complex which interacts with the TGF type I receptor.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human TGF-beta RI Protein, Fc Tag (TG1-H5254) is expressed from human 293 cells (HEK293). It contains AA Leu 34 - Leu 126 (Accession # P36897-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: TGF-beta RI
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Leu 34 - Leu 126
Swiss-prot: P36897-1
Package Size: 500ug*2
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 36.7 kDa. The protein migrates as 43-48 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 36.7 kDa
Shipping Condition: RT
Species Reactivity: Human
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