Recombinant Human G-CSF

DESCRIPTION

G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.

DETAILS

Gene Id: 1440
Uniprot: P09919
Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^7 units/mg.
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: AIDS/HIV, Angiogenesis/Cardiovascular, Cancer, Diabetes/Weight Regulation, Immune System, Inflammation, Stem Cells and Differentiation
Alternative Names: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFbeta, pluripoietin
Species of Origin: Human
Expression System Source: E.coli