DESCRIPTION

• Aa: 2-58
• Mw: 32 kDa
• Tags: N-terminal GST-tag
• Format: Aqueous buffer solution
• Genbank: NM_003532
• Species: Human
• Uniprot: P68431
• Shiptemp: -80°C (dry ice)
• Synonyms: Histone 3.1, HIST1H3E
• Warnings: Avoid freeze/thaw cycles.
• Category: Methyltransferase/Substrates
• References: 1. Loyola, A. et al., Mol. Cell 24 (2), 309-316 (2006). 2. Groth, A. et al., Mol. Cell 17 (2), 301-311 (2005). Application Reference(s): Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)
• Description: Human Histone 3 (GenBank Accession No. NM_003532), a.a. 2-58 with N-terminal GST-tag, MW = 32 kDa, expressed in an E. coli expression system.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol, and 3 mM DTT.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful as a substrate for methyltransferases or acetyltransferases and for screening small molecular inhibitors of histone methyltransferases for drug discovery.
• Product Type: Protein
• Host Cell Line: E. coli
• Biosafety Level: Not applicable (BSL-1)
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Methyltransferase