Human CD24 Protein, His Tag (Nanoparticle)

DESCRIPTION

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 1mg
Buffer: PBS with glycine and sodium citrate, pH8.0
Format: Powder
Purity: 90%
Source: Human CD24 Protein, His Tag (CD4-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: CD24
Accession: NP_001278666.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ser 27 - Gly 59
Swiss-prot: P25063-1
Package Size: 1mg*1
Characteristics: Human CD24 Protein, His Tag is designed and expressed as nanoparticles of approximately 25 nm diameter by displaying CD24 ECD in native conformation. The nanoparticles each was coated with an average of 180 CD24 ECD. The nanoparticle technology allows directional and high-density display of human CD24 on the surface of nanoparticles, thus greatly enhances the immune response in vivo to otherwise poorly immunogenic epitopes. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 43-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.5 EU per μg
Molecular Weight: 34.3 kDa
Shipping Condition: RT
Species Reactivity: Human
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