LG4-H52H3-100ug LG4-H52H3-1mg
Human LGR4 / GPR48 protein, His Tag
ACROBiosystems
DESCRIPTION
Human LGR4, His Tag (LG4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 25 -Thr 544 (Accession # Q9BXB1-1).
DETAILS
- Tag: C-10×His
- Host: HEK293
- Size: 100ug
- Buffer: PBS, pH7.4
- Format: Powder
- Purity: 85%
- Storage: -20℃
- Category: Other Recombinant Proteins
- Molecule: LGR4
- Accession: NP_060960.2
- Conjugate: Unconjugated
- Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Background: The fourth member of the leucine-rich repeat-containing GPCR family (LGR4, frequently referred to as GPR48) together with its family members LGR5 and -6, bind to R-spondins (RSPOs)-1–4 and result in Wnt signaling potentiation. In addition, LGR4 (as well as LGR5 and -6) is implicated in multiple cancers and promotes invasion and metastasis in colorectal, prostate, and cervical cancer cell lines.
- Exp Region: Ala 25 -Thr 544
- Swiss-prot: Q9BXB1-1
- Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.8 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level: 1.0 EU per μg
- Molecular Weight: 58.8 kDa
- Shipping Condition: RT
- Species Reactivity: Human
- Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html