Human CD40 Ligand / TNFSF5 Protein, Fc Tag (N297A), active trimer, premium grade

DESCRIPTION

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]

DETAILS

Tag: N-Fc
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Human CD40 Ligand Protein, Fc Tag (N297A), premium grade (CDL-H5264) is expressed from human 293 cells (HEK293). It contains AA Gly 116 - Leu 261 (Accession # P29965-1).
Storage: -20℃
Category: Immune Checkpoint Proteins
Molecule: CD40 Ligand
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gly 116 - Leu 261
Swiss-prot: P29965-1
Package Size: 100ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 74.5 kDa. The protein migrates as 81 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 0.01 EU per μg
Molecular Weight: 74.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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