Mouse IL-31 RA Protein, Fc Tag

DESCRIPTION

Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.

DETAILS

Tag: C-Fc
Host: HEK293
Size: 100ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Mouse IL-31 RA Protein, Fc Tag (ILA-M5254) is expressed from human 293 cells (HEK293). It contains AA Val 19 - Thr 499 (Accession # Q8K5B1-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: IL-31 RA
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Val 19 - Thr 499
Swiss-prot: Q8K5B1-1
Package Size: 100ug*1
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 81.6 kDa. The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 81.6 kDa
Shipping Condition: RT
Species Reactivity: Mouse
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