DESCRIPTION

• Aa: 2-595 (full length)
• Mw: 68 kDa
• Tags: N-terminal His-tag
• Genbank: NM_002831
• Species: Human
• Uniprot: P29358
• Shiptemp: -80°C (dry ice)
• Synonyms: HCP, HCPH, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, PTPN6
• Warnings: Avoid multiple freeze/thaw cycles.
• Category: Protein Phosphatase/Non-Receptor
• References: 1. Oka, T. et al., Cancer Research. 62(22): 6390-6394 (2002). 2. Chim, C. S. et al., Blood. 103(12): 4630-4635 (2007).
• Description: Human SHP1 also known as, HCP, HCPH, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, and PTPN6 GenBank Accession No. NM_002831, a.a. 2-595 (full length) with N-terminal His-tag, expressed in an E. coli cell expression system. MW =68 kDa.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween20, 20% glycerol, 3 mM DTT, and 22 0mM Imidazole.
• Supplied As: Aqueous buffer solution.
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Assay Conditions: Enzyme reaction (50 µl) containing 20 mM HEPES, pH 7.4, 100 mM NaCl, 2 mM EDTA, 2 mM DTT, 1 mM pNPP and 0-8000 ng SHP-1. Activity monitored at 415 nm continuously with readings at 1-minute intervals for 20 minutes.
• Related Products: 50272, 60621, 100054, 100080
• Specific Activity: 6.6 pmole/min/µg
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: PTP