T10895
CSN5i-3
TargetMol
DESCRIPTION
CSN5i-3 is a novel potent oral and selective CSN5/Jab1 inhibitor that inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM.CSN5i-3 exhibits anticancer activity, inhibits cell proliferation and induces apoptosis in human breast cancer cells.
DETAILS
- Cas: 2375740-98-8
- Purity: 99.83%
- Smiles: O[C@@H]1[C@H](C2=C(C=C(NC(=O)C=3N(C(C)C)N=C(C(F)F)C3)C=C2)C4=CC=CC=C4)N5C(=CN=C5)CCC1
- Category: Compound
- Molecular Weight: 505.56
- Molecular Formula: C28H29F2N5O2
Lead Time: 4 - 5 weeks
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