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Human Transmembrane Channel-like Protein 1, TMC1 ELISA Kit

Bioassay Technology Laboratory


Transmembrane channel-like protein 1 is a protein that in humans is encoded by the TMC1 gene. TMC1 contains six transmembrane domains with both the C and N termini on the endoplasmic side of the membrane, as well as a large loop between domains 4 and 5. This topology is similar to that of transient receptor potential channels (TRPs), a family of proteins involved in the perception of senses such as temperature, taste, pressure, and vision. TMC1 has been located in the post-natal mouse cochlea, and knockouts for TMC1 and TMC2 result in both auditory and vestibular deficits (hearing loss and balance issues) indicating TMC1 is a molecular part of auditory transduction.


  • GeneID: 117531
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 87,768
  • Synonyms: DFNA36;DFNB11;DFNB7;TMC1;Transmembrane Channel-like protein 1;Transmembrane cochlear-expressed protein 1
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: TMC1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 7.43ng/L
  • Target Protein: TMC1
  • Detection Range: 15-3000ng/L
  • Full Product Name: Transmembrane Channel-like protein 1
  • Standard Solution: 3200ng/L
  • UniProt Accession: Q8TDI8