E6310Hu
Human Transmembrane Channel-like Protein 1, TMC1 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Transmembrane channel-like protein 1 is a protein that in humans is encoded by the TMC1 gene. TMC1 contains six transmembrane domains with both the C and N termini on the endoplasmic side of the membrane, as well as a large loop between domains 4 and 5. This topology is similar to that of transient receptor potential channels (TRPs), a family of proteins involved in the perception of senses such as temperature, taste, pressure, and vision. TMC1 has been located in the post-natal mouse cochlea, and knockouts for TMC1 and TMC2 result in both auditory and vestibular deficits (hearing loss and balance issues) indicating TMC1 is a molecular part of auditory transduction.
DETAILS
- GeneID: 117531
- Species: Human
- Storage: 2-8ºC
- MASS(Da): 87,768
- Synonyms: DFNA36;DFNB11;DFNB7;TMC1;Transmembrane Channel-like protein 1;Transmembrane cochlear-expressed protein 1
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: TMC1
- Reactivity: Human
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 7.43ng/L
- Target Protein: TMC1
- Detection Range: 15-3000ng/L
- Full Product Name: Transmembrane Channel-like protein 1
- Standard Solution: 3200ng/L
- UniProt Accession: Q8TDI8