SF3B14 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 51639
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: SF3B6
Other Names: Splicing factor 3B subunit 6, Pre-mRNA branch site protein p14, SF3b 14 kDa subunit, SF3B14a, Spliceosome-associated protein, 14-kDa, Splicing factor 3b, subunit 6, 14kDa, SF3B6, SAP14, SF3B14, SF3B14A
Availability: 2 weeks
Bio Background: SF3B14 encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Bio References: Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Schellenberg, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(5):1266-1271(2006)
Primary Accession: Q9Y3B4