30-2449
Anti-CD16 / FcgammaRIII Monoclonal Antibody (Clone:3G8)-PerCP Conjugated
Abeomics
DESCRIPTION
CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgammaRIII is expressed in two forms - FcgammaRIII-A and -B. FcgammaRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgammaRIII-A is associated, moreover, with FcepsilonRI-beta subunit. Besides IgG, FcgammaRIII-A can be triggered also by oligomeric IgE. FcgammaRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
DETAILS
- Gene: FCGR3A
- App Id: FACS, IP, IHC-Fr, Functional Assay
- Antigen: CD16
- Gene Id: 2214
- Isotype: Mouse IgG1
- Clone Name: 3G8
- Uniprot Id: P08637
- Host Animal: Mouse
- Clonality Id: Monoclonal
- Conjugate Id: PerCP
- Reactivity Id: Human, Non-Human Primates
- Alternative Name: FCGR3A||CD16A||FCG3||FCGR3||IGFR3
- Storage Condition: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
- Immunogen Information: Human neutrophils