Human CLEC12A / MICL / CLL-1 Protein, His Tag

DESCRIPTION

CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.

DETAILS

Tag: N-10×His
Host: HEK293
Size: 50ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Human CLEC12A, His Tag (CLA-H5245) is expressed from human 293 cells (HEK293). It contains AA His 65 - Ala 265 (Accession # Q5QGZ9-2).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: CLEC12A
Accession: NP_612210.4
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: His 65 - Ala 265
Swiss-prot: Q5QGZ9-2
Package Size: 50ug*1
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.6 kDa. The protein migrates as 35-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 25.6 kDa
Shipping Condition: RT
Species Reactivity: Human
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