p1305-241t p1305-241
Promo Available
Anti-Munc18-1 (Ser241) Antibody
PhosphoSolutions
DESCRIPTION
Our Anti-Munc18-1 (Ser241) rabbit polyclonal phosphospecific primary antibody from PhosphoSolutions is produced in-house. It detects mouse and rat Munc18-1 (Ser241) and is antigen affinity purified from pooled serum. It is great for use in WB, IHC.
DETAILS
- Form: Antigen Affinity Purified from Pooled Serum
- Gene: STXBP1
- Host: Rabbit
- Rrid: AB_2492155
- Type: Primary Antibody
- Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
- Target: Munc18-1 (Ser241)
- Isotype: IgG
- Storage: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
- Shipping: Blue Ice
- Synonyms: FLJ37475 antibody, Munc 18 1 antibody, Munc 18a antibody, MUNC18 1 antibody, N-Sec1 antibody, Neuronal SEC1 antibody, NSec1 antibody, p67 antibody, Protein unc-18 homolog 1 antibody, Protein unc-18 homolog A antibody, Rb sec1 antibody, RBSEC1 antibody, STXB1_HUMAN antibody, STXBP1 antibody, Syntaxin binding protein 1 antibody, Syntaxin-binding protein 1 antibody, Unc 18 homolog antibody, Unc 18A antibody, Unc-18A antibody, Unc18 1 antibody, UNC18 antibody, Unc18-1 antibody
- Clonality: Polyclonal
- Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser241 of mouse Munc18-1, conjugated to keyhole limpet hemocyanin (KLH).
- Expiration: After date of receipt, stable for at least 1 year at -20°C.
- Specificity: Specific for endogenous levels of the ~65 kDa Munc18-1 protein phosphorylated at Ser241. Immunolabeling is completely eliminated by treatment with λ-phosphatase.
- Applications: WB, IHC
- Ncbi Gene Id: 20910
- Conjugate Exem: Unconjugated
- Physical State: Liquid
- Quality Control: Western blots performed on each lot.
- Usage Statement: For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
- Molecular Weight: 65
- Production Notes: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
- Dilution Range Wb: 1:1000
- Immunogen Species: Mouse
- Dilution Range Ihc: 1:500
- Species Reactivity: Mouse and Rat
- Target Description: Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc18-1 is thought to be regulated by phosphorylation.
- Expected Reactivity: Bovine, Canine, Chicken, Human, Non-Human Primate, Sheep
- Dilution Range Wb Brain: 1:1000
- Uniprot Number Immunogen Species: O08599
- Post Translational Modification Type: Phosphorylated
- Post Translational Modification Residue: Ser241
PROMOTION TERMS
Trial Size Available. Limit 1
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