Anti-SOX9 / SRY-box 9 Monoclonal Antibody(Clone: SOX9/2287R)

DESCRIPTION

The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) [MIM:114290]: Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common.

DETAILS

Gene: SOX9
App Id: ELISA,WB
Gene Id: 6662
Isotype: Rabbit IgG
Clone Name: SOX9/2287R
Uniprot Id: P48436
Host Animal: Rabbit
Clonality Id: Monoclonal
Reactivity Id: Human
Product Content: 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Alternative Name: CMD 1; campomelic dysplasia autosomal sex reversal; SRA1; SRXX2; SRXY10; SRY (sex determining region Y) box 9; SRY related HMG box gene 9; Transcription factor SOX 9
Application Note: ELISA (For coating, order antibody without BSA);,Western Blot (1-2ug/ml);,
Categories Name 1: Antibodies
Categories Name 2: Cancer Marker
Storage Condition: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Immunogen Information: Recombinant human full-length SOX9 protein